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Nancy Hopkins is an Amgen Professor of Biology Emerita at the Massachusetts Institute of Technology (MIT). Her research has focused on genetics, utilizing mouse models and RNA tumor viruses to explore genetic influences on early vertebrate development, particularly using zebrafish as a model for cancer research. During her tenure as an assistant professor at MIT’s Center for Cancer Research, she contributed significantly to understanding the genetic mapping of RNA tumor virus genes, identifying critical genes that determine host range and the type and severity of cancers caused by mouse retroviruses. She has developed tools for zebrafish research, including a method for large-scale insertional mutagenesis that has enabled the identification and cloning of 25% of the essential genes required for a fertilized zebrafish egg to develop into a swimming larva. Presently, her work is oriented towards advocacy for cancer prevention and early detection research.