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Nathalie Oulhen is an Assistant Professor in the fields of Molecular Biology, Cell Biology, and Biochemistry. Her research focuses on the quiescence phenotypes of stem cells, particularly in relation to primordial germ cells (PGCs) in sea urchin embryos. Oulhen's studies have revealed that PGCs exhibit a distinct quiescent state during embryonic development, characterized by a reduction in overall translational and transcriptional activity, as well as decreased mitochondrial function. These characteristics differentiate PGCs from their somatic cell counterparts, which divide and transcribe rapidly post-fertilization. Oulhen's work emphasizes the transient nature of quiescence in PGCs, noting that they resume significant metabolic activities during gastrulation. Her ongoing research seeks to understand the mechanisms regulating the entry, maintenance, and exit of quiescent states in embryonic development, aiming to elucidate fundamental processes associated with stem cell biology.
Department: Department of Economics