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Neil Brockdorff is a professor in the Department of Biochemistry at the University of Oxford. His research focuses on the molecular mechanisms of X chromosome inactivation, a crucial process for equalizing gene expression between XX females and XY males in mammals. His early studies identified the specialized RNA molecule Xist, which plays a key role in regulating X-inactivation by accumulating on the inactivated X chromosome and recruiting factors that modify the chromatin. His ongoing work involves the fields of embryology, genetics, cell biology, molecular biology, and biochemistry, employing advanced methodologies such as genome and proteome engineering, super-resolution imaging, live-cell ultrastructural imaging, and high-throughput sequencing techniques, including RNA-seq and ChIP-seq.
University of Oxford • Oxford, ENG, GB
Teaching and researching in the field of biochemistry with a focus on gene regulation and X chromosome inactivation.
Department of Politics and International Relations - Higher Level English requirement.