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Nelson Ruiz-Opazo is a Professor at Boston University, specializing in molecular genetics and the mechanisms of hypertension and related organ complications. His research focuses on the dual endothelin-1/signal peptide VEGF receptor (DEspR) as a novel therapeutic target in cancer and other pathologies, including cancer stem cell (CSC) behavior and tumorigenicity. He employs interdisciplinary collaborations to enhance translational research, particularly regarding the roles of DEspR+ neutrophils in conditions such as acute respiratory distress syndrome (ARDS) and herpes-induced intracerebral hemorrhage (ICH). Dr. Ruiz-Opazo has extensive experience in xenograft modeling with CSCs and has conducted survival analysis for assessing the efficacy and safety of targeted therapies addressing high unmet medical needs, particularly in cancers like pancreatic adenocarcinoma and glioblastoma. His academic contributions span both fundamental molecular genetics and applied applications in clinical settings, showcased through various grants and notable projects focusing on genetic determinants of hypertension and their implications for human health.
Boston University • Boston, MA
Conducts research and teaches in molecular genetics, focusing on hypertension and cancer.
Department of Law offers JD, LLM, and Master's in Study of Tax Law.