Dr. Nicholas Hand

Biography

Nicholas J. Hand is a Research Associate Professor in the Department of Genetics at the Perelman School of Medicine, University of Pennsylvania. He is a molecular biologist with a focus on diseases affecting the liver, including cholestatic liver disease and metabolically-associated steatotic liver disease. His research employs advanced techniques such as CRISPR/Cas9 genome editing and stem cell-derived models to understand gene expression regulatory mechanisms and the molecular basis of liver dysfunction. Over the years, Dr. Hand has developed a significant body of work that investigates the role of microRNAs in liver disease and cholesterol metabolism. He has extensive training as a postdoctoral fellow and has held various academic positions within notable institutions, collaborating on multiple high-impact studies in genetics and disease. The focus of his current research includes linking genetic variants to functional consequences through genome-wide and phenome-wide association studies. Dr. Hand's outstanding contributions to the field have been recognized through various publications in high-impact journals and by his leadership within collaborative research groups.

Research Interests

Experience