Dr. Nick Coleman

Biography

Professor Nick Coleman is the Head of the Division of Cellular and Molecular Pathology at the University of Cambridge. His research primarily focuses on the mechanisms of cervical neoplastic progression and the genetic underpinnings of malignant germ cell tumors in pediatric cancers. Notably, his group is investigating early events in the development of cervical carcinoma with the aim of improving the identification of pre-cancers and understanding the effects of current treatments. Additionally, he is exploring new therapeutic strategies targeting high-risk human papillomavirus oncogenes. His lab has developed a unique in vitro longitudinal model of cervical carcinogenesis using the W12 cell line system and has established a significant archive of frozen cervical tissue. Professor Coleman's work has led to important findings related to the role of microRNAs in malignant germ cell tumors, and he is currently developing clinical protocols for serum microRNA testing in childhood cancer diagnosis and monitoring. His contributions to the field are further underscored by collaborations with major cancer research groups, including the UK Children’s Cancer and Leukaemia Group.

Research Interests