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Dr. Nicola Jones is a Professor in the Department of Physiology at the University of Toronto, focusing on the interplay between enteric microbes and host immune responses with an emphasis on disease pathogenesis. Her research primarily examines the gastric pathogen Helicobacter pylori, which infects approximately 50% of the global population and is linked to the development of peptic ulcers and gastric cancer. Dr. Jones investigates the mechanisms by which H. pylori evades host immune responses, leading to chronic infection and disease progression. A significant aspect of her work involves understanding inflammatory bowel disease, where she explores how genetic susceptibility alters autophagy responses to intestinal microorganisms. Her laboratory employs various methodologies, including cell culture, immunohistochemistry, and gene expression analysis, to elucidate the pathways contributing to these diseases. She is actively involved in mentoring trainees and collaborates with scientists both within and outside her department.
Department of Physiology, University of Toronto • Toronto, ON, Canada
Leading research and academic activities in the field of physiology, focusing on microbial-host interactions and disease mechanisms.
Department of Sociology