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Nicole M. Martinez is an Assistant Professor in the Department of Chemical Systems Biology and the Department of Developmental Biology at Stanford University. Her scholarly interests encapsulate RNA-based mechanisms of gene regulation, focusing on the precise control of gene expression levels and the processing of messenger RNA, which is critical for organismal development and response to environmental cues. Dysregulation of these processes can lead to a variety of diseases. Her research delves into uncovering the mechanisms that govern alternative mRNA processing and its downstream effects on gene expression and cell physiology. Additionally, she investigates the extensive modifications that eukaryotic mRNA undergoes, including the impact of non-canonical bases on pre-mRNA processing steps such as splicing and 3’ end processing. The dysregulation of RNA-modifying enzymes is linked to a wide spectrum of human diseases, making it essential to elucidate this new layer of gene regulation. Her current work integrates molecular biology, biochemistry, genomics, genetics, and systems biology to further understand these mechanisms and their relevance in development and disease.
The Computer Science department emphasizes research potential. GRE General is currently optional but recommended for some tracks.