Dr. Nicole Prior

Biography

Nicole Prior is a Lecturer in Stem Cell Biology at the University of Southampton. Her research focuses on understanding genomic metabolic networks that underpin liver progenitor differentiation and adult homeostasis. She employs 3D organoid systems to investigate liver development and regeneration. Her work emphasizes the importance of temporal and spatial regulation of differentiation, integrating various metabolic signals essential for cell fate transitions. Prior aims to dissect the genetic and metabolic signals influencing the differentiation of liver progenitor cells into hepatocytes and ductal cells. She utilizes both human and mouse models in her research to characterize metabolic changes associated with liver differentiation, and to understand how metabolic rewiring can affect cellular decisions. Prior's previous roles include Postdoctoral Research Fellow at the University of Cambridge and the European Molecular Biology Laboratory. She completed her PhD in Developmental Biology at the European Molecular Biology Laboratory/Heidelberg University and holds a Bachelor of Science in Biological Sciences from the University of Warwick.

Research Interests

Experience