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Nikki Lee is a lecturer at the University of Sydney in the School of Life and Environmental Sciences, having completed her PhD at the University of New South Wales in 2009. Her doctoral research focused on the role of neuropeptide Y (NPY) Y1 receptor in controlling bone mass and involved mentorship from Professor Herbert Herzog at the Garvan Institute of Medical Research. As a post-doctoral researcher, she identified osteoglycin, a novel bone-derived hormone that affects glucose homeostasis and energy expenditure in insulin-target tissues, which led to successful NHMRC grant applications in 2018 and 2020. In 2022, Lee became an NHMRC research fellow at the School of Medical Sciences within the Charles Perkins Centre at the University of Sydney. Her research addresses the interaction between obesity, type 2 diabetes, and osteoporosis, focusing on neuropeptide pathways that govern energy partitioning between fat storage and bone building. Lee's work aims to develop innovative methodologies to dissect the leptin/NPY axis, elucidating mechanisms that control energy distribution and potentially uncovering new treatment avenues for metabolic disorders. Her recent projects include a NHMRC Ideas grant investigating leptin's interactions with NPY neurons, and exploring sex differences in energy homeostasis regulation as well as metabolic abnormalities in neurodegenerative disease patients.
University of Sydney • Sydney
Lecturer in the School of Life and Environmental Sciences, focusing on neuropeptide pathways and their role in energy partitioning and metabolic health.
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