Professor Dr. Nynke Dekker

Biography

Nynke Dekker is a leading researcher at Oxford University focusing on single-molecule biophysics, particularly in understanding the real-time functions of DNA and RNA associated molecular motors. Her lab employs high-precision techniques including single-molecule fluorescence and magnetic optical tweezers, along with integrated force-fluorescence spectroscopy, to visualize the dynamics of replisome assembly, replication fork progression, and chromatin interactions. Dekker explores various aspects of replication across eukaryotes, bacteria, and viruses, investigating the role of accessory proteins and nucleosomes, as well as potential obstacles that impact replication fidelity. Her work bridges the fields of physics, biochemistry, and molecular biology, providing mechanistic insights into replication dysregulation and its connection to disease.

Research Interests