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Oleta Johnson is an Assistant Professor in the Department of Chemistry at the Massachusetts Institute of Technology. Her research focuses on the role of molecular chaperone proteins in supporting proper protein folding and mitigating the pathological aggregation events that are hallmark features of various myopathies and neurodegenerative diseases. The dysfunction of these chaperone proteins under specific circumstances can lead to significant health issues, including Huntington’s Disease and Parkinson’s Disease. To better understand the molecular underpinnings of chaperone function and dysfunction, her laboratory employs a combination of chemical biology, biophysics, and biochemistry approaches. They aim to uncover the core structure-function relationships of conformationally dynamic molecular chaperones and to discover strategies that can activate chaperone functions to treat protein misfolding diseases.