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Professor Owen Sansom is the Director of the Institute of Cancer Sciences at the University of Glasgow and is renowned for his research in colorectal cancer. His work focuses on the Wnt signalling pathway and its implications in early changes associated with intestinal neoplasia, aiming to identify novel markers of the disease and new therapeutic targets. With a significant percentage of sporadic colorectal cancers linked to mutations in the Apc gene, Professor Sansom's research has delved into understanding the germline heterozygosity of Apc leading to Familial Adenomatous Polyposis. He utilizes innovative inducible models of intestinal tumorigenesis to study the roles of specific tumor suppressor genes, which has critical implications for cancer evolution and novel therapies. His contributions are widely recognized, and he has secured numerous grants to advance cancer research, addressing areas from metabolic drivers of cachexia to the effects of circadian rhythms on metastasis.
Institute of Cancer Sciences, University of Glasgow • Glasgow, Scotland
Leading the Institute of Cancer Sciences with a focus on colorectal cancer and innovative therapies.