Dr. Owen Witte

Biography

Owen Witte is a University Professor in the UC system and holds the President's Chair in Developmental Immunology. He is affiliated with the Department of Microbiology, Immunology, and Molecular Genetics, and serves as the Director of the Eli Edythe Broad Center of Regenerative Medicine and Stem Cell Research. His research focuses on cancer pathogenesis and the immune response, with significant contributions towards defining new therapeutic targets. Witte's pivotal work in endocrine signaling, particularly through the family of tyrosine kinase enzymes, has provided insights into diseases such as Chronic Myelogenous Leukemia and has contributed to the development of targeted therapies like Imatinib and Ibrutinib. His ongoing research investigates epithelial cancers, including prostate cancer, exploring cancer-specific antigens and their role in immune response. Witte is committed to understanding the normal development of the prostate and how this knowledge can be applied to the complexity of cancer progression and metastasis. By employing advanced imaging technologies such as Positron Emission Tomography, he aims to monitor and elucidate tumor-immune interactions and cellular metabolism. His impactful findings have been published in high-profile journals and reflect a dedication to innovative cancer research.

Research Interests

Experience