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Panayiotis O. Vacratsis is an Associate Professor in the Department of Chemistry and Biochemistry at the University of Windsor. He earned his Ph.D. from Michigan State University. His research focuses on cellular signaling mechanisms, particularly the regulation of phosphorylation processes by kinases and phosphatases which play crucial roles in cellular responses to extracellular signals. His laboratory utilizes a combination of biological mass spectrometry and traditional biochemical techniques to explore the intricacies of signal transduction pathways that govern essential processes such as cell survival and cellular differentiation. Vacratsis has identified key regulatory mechanisms that influence the cellular localization and activity of various phosphatases, including the novel dual specificity phosphatase hYVH1, which is vital for ribosome biogenesis and is implicated in various cancers due to its overexpression in malignant tissues. His innovative approach also involves investigating mutations in the lipid phosphatase MTMR2 that are linked to Charcot-Marie-Tooth disease, contributing to a better understanding of how these mutations disrupt normal cellular function and promote disease.
University of Windsor • Windsor, Ontario, Canada
Teaching and conducting research in the field of Biochemistry, with a focus on cellular signaling and phosphorylation mechanisms.
Includes Mechanical, Automotive, and Materials Engineering streams.