Dr. Paola Marignani

Professor

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Biography

Paola Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University. Her research interests focus on tumor suppressors, cancer metabolism, signal transduction, and pre-clinical drug studies aimed at understanding the molecular basis of diseases. The Marignani Lab engages in fundamental research to discover tumor suppressor proteins and their roles in maintaining cellular equilibrium, aiming to translate findings into effective treatments. Marignani has published extensively in the field of cancer biology, revealing insights into the mechanisms by which environmental chemicals enable cancer progression and how mutations in tumor suppressor genes impact disease. Her lab provided substantial contributions to the understanding of LKB1, a key tumor suppressor involved in multiple malignancies. Marignani is also dedicated to mentoring future scientists and has been instrumental in developing educational programs for graduate and medical students. Her leadership in the lab has fostered numerous research collaborations and innovations in cancer therapy.

Research Interests

Experience

Professor

2003-01-01 — Present

Dalhousie University • Halifax, Nova Scotia, Canada

Leading research on cancer biology and mentoring students.

Postdoctoral Fellow

2002-01-01 — 2003-01-01

Harvard University • Cambridge, Massachusetts, USA

Conducted advanced research in cancer signaling mechanisms.