Professor Dr. Pascal Chartrand

Biography

Pascal Chartrand is a Full Professor at the Université de Montréal, specializing in the biochemistry and molecular medicine as part of the Faculty of Medicine. His research primarily focuses on the intracellular trafficking of telomerase RNA and its role in biogenesis, regulation, and activity. He studies the implications of telomerase in cancer, particularly regarding its reactivation in most cancers allowing for the immortalization of cancer cells. His laboratory uses single-molecule imaging techniques to explore the mechanisms of telomerase RNA trafficking and the regulation of telomerase activity by non-coding RNAs in the context of myotonic dystrophy type 1 (DM1). In addition, he investigates mechanisms of intracellular mRNA transport and its role in the localized translation of proteins in polarized cells, which is crucial for developmental processes in multicellular organisms. Chartrand has received several accolades, including the FRQS Research Chair and various Senior and Junior Researcher awards from FRSQ and FCAR. He is actively involved in supervising graduate students and contributing to multiple research projects that aim to advance understanding in molecular biology and gene regulation.

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