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Pascale Daran-Lapujade's research is dedicated to understanding the complexity of biological systems, particularly focusing on how microbes respond to their environments. Her work prominently features the model eukaryote, industrial yeast Saccharomyces cerevisiae, alongside a growing interest in 'non-conventional' yeasts. Major research themes encompass the study of central carbon metabolism regulation and the uncoupling of growth and product formation. The projects draw upon a diverse array of methodologies, including quantitative physiology, genomics, and cell biology, leveraging tools such as molecular biology techniques, cultivation in bioreactors, transcriptome analysis, fluorescent microscopy, and fluorescence-activated cell sorting (FACS). Recognizing the limitations of genetic studies in S. cerevisiae, she ventured into synthetic biology, establishing a new research line focused on creating a yeast platform for rapid and efficient remodeling of essential metabolic pathways. This ambitious endeavor has gained significant support, including an ERC Consolidator grant. Since June 1, 2021, she has been the Director of the Graduate School of the Applied Sciences, which comprises around 500 PhD candidates, and has served as a senior editor for the international journal FEMS Yeast Research since 2014.
Graduate School of the Applied Sciences • Delft
Oversees and manages PhD candidates and their academic progress.
Delft University of Technology • Delft
Leading research in the field of biotechnology with a focus on synthetic biology and microbial metabolism.
Requirements apply generally across engineering and science master programs. Specific tracks like Architecture require a digital portfolio.