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Pascale Legault is a leading researcher in RNA molecular medicine, focusing on the fundamental biochemical processes governed by specific RNA/RNA and RNA/protein interactions. Her work investigates RNA's roles in various mechanisms, including RNA cleavage, regulation of translation, modification, and splicing. Additionally, she studies the implications of RNA-related processes in viruses like hepatitis C, HIV, and SARS-CoV. Pascale employs NMR spectroscopy and other biophysical methods to explore RNA structure and function. Her research aims to enhance understanding of RNA structural recognition to inform drug design for cancer and viral treatments. She has been instrumental in several key projects, emphasizing structural studies and functional genomics, and has supervised numerous graduate theses at the doctoral and master’s levels.
Université de Montréal • Montréal, QC, Canada
Leading the Department of Biochemistry and Molecular Medicine.
Department of Pharmacology and Physiology - Research intensive with options in Neuropharmacology and Pharmacogenomics.