Dr. Patrick O Brien

Professor

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Biography

Patrick O'Brien is a Professor in the Department of Biological Chemistry at the University of Michigan Medical School. His research focuses on molecular mechanisms involved in DNA repair, replication, and mutagenesis. O'Brien utilizes biochemical, biophysical, and genetic cellular approaches to explore the basic mechanisms that preserve genetic integrity in normal tissues and the abnormalities that may drive cancer, immunodeficiency, and aging. His lab, known as the O'Brien Lab, is a member of the Rogel Cancer Center, which emphasizes collaboration and innovation in cancer research. O'Brien has contributed significantly to the field through various scholarly articles, highlighting his expertise in DNA ligase functions, the impact of genetic variations on reproductive fitness, and the interactions between chemotherapy and germline mutations. He is committed to mentoring the next generation of scientists while also advocating for advancements in cancer research and treatment. O'Brien's extensive publication record reflects his active engagement in addressing critical issues in molecular biology and genetics.

Research Interests

Experience

Associate Chair

2022-01-01 — Present

University of Michigan Medical School • Ann Arbor, MI

Responsible for overseeing the biological chemistry department and managing research initiatives.

Requirements for University of Michigan Medical School

Doctorate Program
Requirements
GPA Requirement
Required:3
TOEFL
Listening
Required:22
Reading
Required:22
Writing
Required:22
Speaking
Required:22
Total
Required:84
IELTS
Listening
Required:6.5
Reading
Required:6.5
Writing
Required:6.5
Speaking
Required:6.5
Overall
Required:6.5
Prerequisites
Bachelor's degree or equivalent Prior laboratory research experience Significant undergraduate coursework in chemistry and biology
Application Checklist
  • Online Application via Rackham
  • Academic Statement of Purpose
  • Personal Statement
  • Three Letters of Recommendation
  • Official Transcripts
  • CV/Resume
Specialization Notes

Admission for Biological Chemistry, Cellular and Molecular Biology, Human Genetics, Microbiology and Immunology, Pharmacology, Molecular and Integrative Physiology, Cancer Biology, and Neuroscience is primary handled through the PIBS (Program in Biomedical Sciences) gateway.