Professor Dr. Patrick O Brien

Professor

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Biography

Patrick O'Brien is a Professor in the Department of Biological Chemistry at the University of Michigan Medical School. His research primarily focuses on the molecular mechanisms of DNA repair, replication, and mutagenesis. He employs biochemical, biophysical, genetic, and cellular approaches to investigate how normal tissues preserve genetic integrity and how abnormalities in these processes can drive diseases such as cancer and immunodeficiency, as well as the effects of aging. O'Brien's work has contributed significantly to understanding the mechanisms behind DNA damage tolerance and ligase fidelity in various contexts, including neuroblastoma and Huntington's disease. He is an active member of the Rogel Cancer Center and has published numerous articles in leading journals, highlighting his important contributions to the field of molecular biology and genetics.

Research Interests

DNA Repair Replication Mutagenesis Biochemical Approaches Biophysical Approaches Genetic Approaches Cellular Approaches

Experience

Professor

2010-09-01 — Present

University of Michigan Medical School • Ann Arbor, MI, US

Teaching and conducting research in the field of Biological Chemistry.

Requirements for University of Michigan Medical School

Doctorate Program

Requirements

GPA Requirement
Required:3
TOEFL
Listening
Required:22
Reading
Required:22
Writing
Required:22
Speaking
Required:22
Total
Required:84
IELTS
Listening
Required:6.5
Reading
Required:6.5
Writing
Required:6.5
Speaking
Required:6.5
Overall
Required:6.5

Prerequisites

Bachelor's degree or equivalent Prior laboratory research experience Significant undergraduate coursework in chemistry and biology

Application Checklist

  • Online Application via Rackham
  • Academic Statement of Purpose
  • Personal Statement
  • Three Letters of Recommendation
  • Official Transcripts
  • CV/Resume

Specialization Notes

Admission for Biological Chemistry, Cellular and Molecular Biology, Human Genetics, Microbiology and Immunology, Pharmacology, Molecular and Integrative Physiology, Cancer Biology, and Neuroscience is primary handled through the PIBS (Program in Biomedical Sciences) gateway.