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Patrick Sandoz is an Associate Senior Lecturer in the Department of Materials Science and Engineering at Uppsala University. His research focuses on pioneering interdisciplinary approaches to unravel structural complexities and signaling dynamics within cellular microenvironments. He has a specific interest in understanding the architecture and biophysical properties of tumor microenvironments and exploring how these factors influence immune responses, disease progression, and therapeutic outcomes. His work specializes in developing advanced multicellular microphysiological systems that replicate microenvironments with high fidelity, capturing molecular and biophysical signatures. By incorporating biomimetic materials and diverse cell types, his models enable the study of critical processes such as cancer progression, molecular signal diffusion, mechanical stress, immune cell infiltration, and metastatic niche formation. He emphasizes the role of innate-like T cells and γδ T cells in immune responses, highlighting their potential as promising candidates for novel therapeutic strategies. By combining expertise in materials science, microsystem engineering, cancer biology, immunology, and computational modeling, he aims to address the challenges associated with recreating intricate three-dimensional multicellular environments, ultimately advancing personalized therapy development.
General Master's requirements applying across Science, Technology, and Humanities departments.