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Paul D. Friesen is a Professor in the Department of Biochemistry at the University of Wisconsin-Madison, specializing in molecular virology with a strong focus on the study of eukaryotic DNA viruses. His research explores the intricate mechanisms of virus replication, particularly with baculoviruses, which are large DNA viruses pathogenic to invertebrates. These viruses have gained popularity as eukaryotic vectors for high-level expression of foreign proteins. Friesen's lab investigates the control of gene expression during baculovirus replication and the molecular interactions between viral and host cell transcription factors. His work on the apoptotic processes regulated by baculoviruses has significant implications for understanding the regulation of programmed cell death (PCD). His research employs a variety of techniques in molecular virology, including gene cloning, sequencing, and protein purification, to advance the understanding of gene regulation and its applications in developing therapeutic strategies for apoptosis-related diseases.
Department: Department of Computer Sciences