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Paul LaPointe is a professor in the Department of Cell Biology at the University of Alberta. He specializes in the molecular mechanisms of chaperone proteins, particularly the Hsp90 chaperone system, which is critical for the function of many client proteins including kinases and hormone receptors. His research utilizes a combination of genetic and biochemical techniques to investigate the regulatory roles of co-chaperones and the intricate interactions within client protein activation cycles. LaPointe's work emphasizes the importance of Hsp90 in cellular proteostasis and its implications in diseases, notably in oncogenic processes and cystic fibrosis. He has published extensively on the subject, contributing to innovations in understanding the dynamics of chaperone function in both yeast and mammalian systems. As an educator, LaPointe also mentors graduate students and postdoctoral researchers in his lab, fostering an academic environment that encourages exploration and discovery in cell biology.
University of Alberta • Edmonton
Teaching and conducting research in cell biology, with a focus on the Hsp90 chaperone system.
Department: Mechanical Engineering and Engineering Management