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Paul D. Schedl is a Professor of Molecular Biology at Princeton University, specializing in the genetic regulatory mechanisms that control developmental pathways in Drosophila melanogaster. His research focuses on understanding how gene expression is regulated during early development and the mechanisms that maintain developmental decisions. Schedl's notable work includes the study of the binary switch gene Sex-lethal (Sxl), pivotal for sexual dimorphism in fruit flies. He investigates how Sxl regulates the commitment of cells to specific developmental pathways and how this commitment is maintained throughout development. Additionally, his lab explores chromatin structure and its role in regulating homeotic genes, particularly the Abd-B gene within the BX-C complex. Ongoing studies aim to identify the functions of cis-regulatory elements and boundary elements that control gene expression in specific parasegments. Schedl's contributions to the field extend to the establishment of polarity in Drosophila eggs, which is critical for proper axis formation. His lab is dedicated to challenging existing paradigms and advancing the understanding of cell biology, development, and cancer.
GRE scores are not accepted. Ph.D. is the primary degree; students are not required to hold an M.S.E. prior to admission.