Dr. Paul Sharpe

Biography

Paul Sharpe graduated with a degree in biology from York University and completed a PhD in biochemistry at Sheffield University. After postdoctoral positions in Sheffield, Wisconsin, and Cambridge, he became a lecturer in molecular embryology at the University of Manchester in 1987, where he established a research group focusing on the molecular control of tooth development. In 1991, he was recruited to Guy's Hospital as Chair of the Dental Institute, which later merged with King's College London, where he established a new basic research department, the Department of Craniofacial Development and Stem Cell Biology, consisting of 15 academic research groups and 80 research staff. In 2017, the department was awarded Centre of Excellence status for Craniofacial Regenerative Biology. From 2002 to 2008, he served as Director of Research at the Dental Institute. His main research interests include the molecular control of tooth development, dental stem cell biology, and tooth bioengineering. He has published over 300 research papers in prestigious journals such as Nature, Science, PNAS, and Cell Press and has supervised 50 PhD students. He is currently receiving funding from MRC, NIHR, and NIH. Additionally, he is a member of the MRC Centre for Transplantation and serves on the MRC Regenerative Medicine Research Committee. In recognition of his contributions to understanding tooth development, he received the Craniofacial Biology Research Award from the International Association for Dental Research in 2004 and the William J. Gies Award for his publications from the Biomaterials Bioengineering Organization in 2006 and 2018.

Research Interests