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Paula Desplats is an Associate Professor in the Department of Neurosciences at the University of California, San Diego. Her research focuses on the molecular mechanisms underlying neurodegenerative diseases, particularly Alzheimer's disease and Lewy body dementia. She investigates the role of circadian dysfunction and epigenetic changes in disease pathogenesis. Desplats is a principal investigator on multiple NIH grants, exploring topics such as DNA methylation and the regulation of oligodendrocyte accumulation of alpha-synuclein in multiple system atrophy. Her lab employs advanced techniques to analyze CNS aging and the impact of HIV on brain health, aiming to uncover novel therapeutic targets for these debilitating conditions.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).