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Pei Zhong is a professor in the Department of Mechanical Engineering and Materials Science at Duke University. His research focuses on engineering and technology development with applications in non-invasive and minimally invasive treatments for kidney stone disease, including shock wave laser lithotripsy, high-intensity focused ultrasound (HIFU) immunotherapy for cancer treatment, as well as acoustic optical cavitation and ultrasound neuromodulation (sonogenetics). Zhong takes an integrated translational approach that combines fundamental research with engineering applied technology development to devise novel ultrasonic, optical, and mechanical tools for a variety of clinical applications. His interests include the interaction of shock waves, lasers, fluids, bubbles, and solids, and the resultant mechanical and thermal fields that can lead to material damage removal. He aims to investigate the stress response of biological cells and tissues induced by cavitation during ultrasound exposure, focusing on mechanosensitive ion channels such as Piezo 1. His research activities are primarily supported by collaborations with the NIH and the medical device industry.
Department of Biomedical Engineering (MS program)