Dr. Pere Puigserver

Biography

Pere Puigserver, Professor of Cell Biology at Harvard Medical School and Dana-Farber Cancer Institute, received his Ph.D. in Biochemistry from the University of the Balearic Islands in Spain. His research has included time at Stockholm University and postdoctoral work at the Dana-Farber Cancer Institute. He joined the faculty of Cell Biology at Johns Hopkins University School of Medicine in 2002 and later returned to Harvard in 2006. His lab focuses on regulatory molecular mechanisms of core metabolic processes that maintain cell homeostasis. Main research areas include mitochondrial biology, intermediary metabolism, and cancer metabolism energetics. Specifically, he investigates mechanisms controlling mitochondrial energetics and biogenesis in relation to various diseases, metabolic and mitochondrial diseases in particular. In intermediary metabolism, his major focus is on how regulatory mechanisms affect nutrient-derived metabolic and energetic activities in liver and adipose cells. His work also addresses processes that drive core cancer biology programs, including cell growth and survival resistance mechanisms. The Puigserver Lab leverages multidisciplinary experimental designs, utilizing chemical genetic screens, quantitative metabolomics, proteomics, biochemistry, and mouse pre-clinical models of obesity, diabetes, mitochondrial diseases, and cancer.

Research Interests

Experience