Dr. Peter Cresswell

Biography

Peter Cresswell is the Eugene Higgins Professor of Immunobiology and a professor of Cell Biology and Dermatology at Yale University School of Medicine. He earned his B.S. in chemistry and M.S. in microbiology from the University of Newcastle Upon Tyne, U.K., followed by a Ph.D. in biochemistry immunology from London University. He completed postdoctoral training at Harvard University under Jack Strominger. Cresswell's research primarily focuses on antigen processing and the mechanisms by which antiviral proteins are stimulated by interferons. His studies center around the MHC class molecules and their interactions with antigen-derived peptides, particularly within the endoplasmic reticulum. His group investigates the peptide loading complex and its components, including TAP and tapasin, focusing on the dynamics of peptide binding and editing processes. Additionally, Cresswell examines the role of CD1d molecules in lipid binding and cross-presentation - critical for the immune system's ability to respond to viral infections. He is a fellow of the Royal Society and a member of several prestigious academies, including the National Academy of Sciences and the American Academy of Arts and Sciences.

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Awards