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Peter Rugg-Gunn is focused on understanding the epigenome during human development and stem cell differentiation. His research examines how epigenetic information changes a person's life course, utilizing various types of stem cells, primarily human pluripotent stem cells, in combination with molecular genetic approaches to characterize and perturb epigenomes. His work includes using stem cell models along with the characterization of mouse and human embryos during the early stages of development. Rugg-Gunn's research is crucial for establishing epigenomes correctly during development, as it has long-lasting health consequences. Additionally, his work provides new insights into improving the epigenetic stability of human pluripotent stem cells, which is essential for driving specialization into useful cell types, meeting the necessary requirements to fulfill the promises of regenerative medicine.
Standard postgraduate requirements for Department of Politics and International Studies (POLIS) and related humanities departments.