Dr. Philip Cole

Biography

Philip Cole is a Professor of Medicine at Harvard Medical School and a renowned researcher in the field of chemical biology, focusing on protein post-translational modifications (PTMs) and their roles in cellular signaling and epigenetics. He received his B.S. in Chemistry from Yale University in 1984 and was a Churchill Scholar at the University of Cambridge before earning his M.D. and Ph.D. degrees from Johns Hopkins University. Following his doctoral studies, Cole completed clinical post-doctoral training at Brigham and Women’s Hospital and joined Rockefeller University in 1996 as a junior lab head. In 1999, he returned to Johns Hopkins as a professor and director of pharmacology until 2017, before moving to Harvard Medical School. His research involves the development and application of chemical approaches to study protein phosphorylation, acetylation, and ubiquitination. He is currently investigating the functions and regulatory mechanisms of key proteins, such as PTEN, Akt, and NEDD4, striving to translate his findings into novel therapeutic opportunities for cancer treatment.

Research Interests