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Deng lab's research aims to deepen understanding of neutrophil biology and offer targeted therapies to change the lives of countless individuals suffering from devastating diseases. Utilizing zebrafish as a model organism, Deng lab is uncovering exciting new genes and signaling mechanisms that govern the migration and activation of neutrophils, the body's powerhouse white blood cells. The research expands understanding of neutrophil function and sheds light on involvement in diseases like cancer, diabetes, ischemia-reperfusion, and neuronal degeneration. Remarkable aspects of Deng lab include successfully validating findings in human neutrophils, meaning discoveries directly relate to human health, paving the way for the development of revolutionary neutrophil-centric therapies. The knowledge gained from zebrafish studies can be harnessed to treat chronic aberrant neutrophil activation diseases, significantly impacting patient care. In addition, by collaborating with Bao lab, Deng lab is pushing boundaries in developing neutrophil products derived from induced pluripotent stem cells. This cutting-edge approach opens a new realm of possibilities for adoptive transfer therapy, with genetically engineered specialized neutrophil products now in the commercialization process to combat solid tumors. The team is working diligently to expand the utility of neutrophil products for significant diseases.
GRE is not required.