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Qiuhong He earned her PhD in physical chemistry from the University of North Carolina at Chapel Hill, focusing on novel electrophoretic nuclear magnetic resonance (NMR) technology. She completed postdoctoral training at Princeton University and subsequently joined the in vivo NMR division of the Department of Radiology at Johns Hopkins University School of Medicine. At Princeton, she conducted intermolecular multiple-quantum coherence transfer (iMQC) experiments, observing novel NMR phenomena related to long-range spin dipolar interactions in solution NMR. At Johns Hopkins, she initiated the development of in vivo magnetic resonance spectroscopic imaging (MRSI) techniques for metabolite detection in tissues with high concentrations of mobile lipids, utilizing a mammary mouse tumor model. As a faculty member, she is developing rapid MRSI techniques for the early detection of human cancer treatment responses, holding several patents in this area. Her recent invention, the pi-MRSI technique, aids in detecting prognostic markers for immunotherapy in cancer patients, as well as differentiating between pseudo-progression and true tumor progression. Additionally, her laboratory has produced genetically engineered anti-cancer bacteria that enhance immunotherapy using mouse models, which are monitored via MRI and optical imaging. She collaborates on projects using machine-learning algorithms for imaging analysis to characterize the effects of bacteria-based cancer treatments.
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