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Rachael Bashford-Rogers is a researcher at the University of Oxford's Medical Sciences Division, focusing on adaptive immunity and clinical translation. Her work investigates the defects in the immune response that lead to susceptibility to infectious diseases and the impaired surveillance of cancer immunodeficiencies. Rachael leads research projects aiming to understand individuals at greater risk of developing immunological diseases, highlighting the key interactions between immune cells at sites of inflammation. She defines novel therapeutic targets and optimal combinations of therapies while identifying blood biomarkers for immune status to stratify patients for improved clinical management. Her research emphasizes translational, patient-focused studies, striving to bridge fundamental biology with early-phase clinical trials. Rachael's interests encompass B cell biology and the interactions of these cells with tissues and blood, focusing on the development and diversification of B cell populations in health and disease. She explores the nature of B cell immuno-surveillance, regulation, and activation in cancers and autoimmune diseases, with a particular emphasis on pancreatic and renal cancers. Furthermore, she investigates minimal residual disease detection in lymphoid malignancies and the influence of genetic and environmental variations on B cell fate while working on immune cell population reconstitution and persistence in immunomodulatory therapy.
Department of Politics and International Relations - Higher Level English requirement.