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Rachel Guest is an Honorary Consultant Hepatopancreatobiliary Surgeon at the Royal Infirmary of Edinburgh and a Senior Lecturer at the University of Edinburgh. She holds a Wellcome Trust Clinical Career Development Fellowship focusing on the molecular mechanisms driving cholangiocarcinoma, commonly known as bile duct cancer. Alongside her clinical responsibilities, she conducts laboratory-based research aimed at understanding the links between liver regeneration and primary liver cancer, particularly cholangiocarcinoma. In collaboration with Professor Ian Tomlinson from the Institute of Genetics & Cancer at the University of Edinburgh, she explores how mutations in the IDH gene influence liver cell identity and contribute to liver tumorigenesis. Rachel completed her higher surgical training in 2019 and was appointed as a consultant surgeon in 2021, with a specific interest in primary liver cancer. She undertook her doctoral research in Professor Stuart Forbes’ lab at the Centre for Regenerative Medicine, focusing on the molecular connections between liver injury, regeneration, and cancer. Rachel has received several awards for her research and academic contributions and is actively involved in various professional panels and editorial boards.
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