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Raghu Vemuganti is a Professor of Neurological Surgery at the University of Wisconsin-Madison, where he serves as Vice Chair of Research at the UW Comprehensive Diabetes Center. His research is focused on deciphering the molecular mechanisms underlying post-stroke brain damage and testing novel therapies to mitigate these effects. He has a particular interest in evaluating the interactive roles of noncoding RNAs (ncRNAs), transcription factors, and epigenetic modifications that modulate pathophysiological events contributing to secondary brain damage. Vemuganti's work also investigates how comorbid conditions like diabetes and hypertension increase stroke vulnerability. To better understand these mechanisms, he uses type-2 diabetic animal models in his experiments. His lab is actively exploring the potential of intermittent fasting as a dietary intervention to promote ischemic tolerance and reduce the occurrence of age-related diseases such as heart attacks, strokes, and dementia by decreasing oxidative stress, inflammation, and mitochondrial damage during recovery from stroke.
Department: Department of Computer Sciences