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Raquel Ordonez Ciriza is a Research Assistant Professor at the Department of Pathology. Her research focuses on synthetic regulatory genomics, genome engineering, systems biology, and sequencing technologies. She investigates the genetic switches that control gene activity, which are crucial for organ formation, tissue repair, and the body’s adaptability to changes. Her work involves creating synthetic versions of regulatory DNA sequences, which can range up to 200 kilobases in length, and inserting these sequences at disease-relevant loci in mammalian genomes using advanced genome engineering techniques. By analyzing the phenotypic effects of these modifications, she explores how regulatory elements interact to influence gene activity. Ordonez Ciriza's ultimate goal is to understand how genetic changes in regulatory DNA contribute to common traits and diseases, uncovering fundamental principles that can advance our knowledge of biology and medicine.
Department of Pathology • New York, NY
Conducts research on synthetic regulatory genomics and genome engineering.
Open Program in Biomedical Sciences (Vilcek Institute) covers departments like Biochemistry, Pathology, Neuroscience, Microbiology, etc.