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Raul Mostoslavsky is a Professor in the Department of Medicine focused on Oncology. His research interests include the role of DNA repair in cancer, aging, and immunodeficiency, particularly the interaction between chromatin structure and metabolic processes. His lab investigates the influence of a group of proteins known as SIRTs on DNA repair and metabolic responses. Notably, SIRT6 has been identified as a key regulator linking chromatin modifications to metabolic adaptation and DNA repair mechanisms. Current projects involve exploring how SIRT6 impacts chromatin structure, cell metabolism, and the relationship between epigenetics and metabolism in cancer cells.
Massachusetts General Hospital • Boston, MA
Leads research in oncology focusing on DNA repair and metabolic functions.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).