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Dr. Raymond William Turner’s work focuses on neuronal membrane excitability studies at molecular physiological levels using animal models. He is exploring new potential therapeutic treatments for the genetic disorder Fragile X Syndrome (FXS). Dr. Turner discovered a fragment missing protein, FMRP, and reintroduced this into the brain using a cell-permeable peptide (tat) that crosses the blood-brain barrier to enter neurons. Remarkably, FMRP N-tat restores ion channel function at the circuit level output (EEG) in a FXS mouse model with a single injection. The success of his work has attracted donor support, leading to the formation of a company (BowensFX) aimed at rapidly advancing fragments towards initial clinical trials to achieve translational outcomes. His research is currently funded by CIHR, NSERC, DCNS/HBI, and FRAXA.
Cumming School of Medicine • University of Calgary, Calgary, Alberta, Canada
Researching neuronal membrane excitability and therapeutic interventions for Fragile X Syndrome.
Department of Computer Science Master's program. GRE scores are expected for international students.