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Rebecca G. Wells, MD, is a Professor in the Department of Medicine at the Perelman School of Medicine, University of Pennsylvania. Her research focuses on the mechanisms of hepatic fibrosis, examining the roles of various mechanical and biochemical factors in the activation of myofibroblast precursor cells and the deposition of extracellular matrix. Her projects include studying liver mechanics, the identity and function of myofibroblast populations, and exploring the impact of liver stiffness on fibrogenesis and liver diseases such as biliary atresia and hepatocellular carcinoma. Wells is also engaged in investigating the signaling pathways involved in liver fibrosis and has contributed to the understanding of chronic liver injury's effects on liver mechanics. Her educational background includes a B.S. in Molecular Biophysics and Biochemistry from Yale University and an M.D. from Johns Hopkins University. Through her research, she aims to develop a comprehensive model of liver fibrosis that integrates various cellular and mechanical factors.
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