Dr. Régis Pomès

Biography

Régis Pomès obtained his PhD in theoretical chemistry under Andy McCammon, specializing in computer simulations of biomolecular systems. After working on the molecular mechanism of proton translocation in ion channels as a postdoctoral researcher with Benoît Roux, he broadened his expertise in computational biophysics in Ángel García's group at Los Alamos. Since moving to Toronto in 1999, he has developed an exciting collaborative research program with a team of talented students and postdocs. His research interests focus on the development of computer simulation techniques and their applications in the studies of ion permeation through membrane proteins, protein-lipid interactions, and a broad range of problems involving solvation, binding, and aggregation of proteins in both folded and disordered states. The Pomès group specializes in the development of computational methods for exploring the link between the structure, dynamics, and function of proteins. Their work is grounded in statistical mechanics, allowing for the connection between microscopic and macroscopic length scales. Using computer simulations and molecular models, they uncover mechanistic insights at spatial and temporal resolutions that are difficult to achieve experimentally, specifically studying systems of biological relevance at atomistic resolution over timescales that extend from femtoseconds to microseconds, covering important biological processes occurring at the molecular level. His research is especially focused on elucidating the physical basis of structure-function relationships in membrane proteins, and addressing a variety of problems related to protein folding, binding, and self-aggregation.

Research Interests

Experience

Awards