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Robert Gordon Kalb, MD, is an Emeritus Professor of Neurology at the Perelman School of Medicine at the University of Pennsylvania, with a clinical focus as an Attending Neurologist at the Philadelphia VA Medical Center. He has extensive experience in treating a broad range of neurological disorders, particularly specializing in the diagnosis and management of patients with Amyotrophic Lateral Sclerosis (ALS). Dr. Kalb's research is centered on understanding the activity-dependent development of central nervous system circuits and the compensatory responses in cells under stress. He employs genetically manipulated mice, primary neuron tissue culture, and studies utilizing the model organism C.elegans. His work examines the molecular mechanisms by which synaptic activity refines neuronal connections necessary for precise behavioral outcomes, identifying critical components such as the SAP97 protein and its role in neurodegenerative processes. Dr. Kalb's contributions have important implications for understanding childhood disorders and adult-onset neurodegenerative diseases.
Philadelphia VA Medical Center • Philadelphia, PA
Board Certified Adult Neurologist with a continuous practice since 1987.
Hospital University of Pennsylvania • Philadelphia, PA
Providing neurological care and expertise within a leading academic medical center.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.