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Robert J. Keenan is a Professor in the Department of Biochemistry and Molecular Biology at the University of Chicago. His research focuses on biochemical reconstitution and the molecular mechanisms underlying the biogenesis and quality control of membrane proteins. He employs approaches from structural biology and cell biology, particularly cryo-electron microscopy, to explore crucial processes within the endoplasmic reticulum (ER). His significant contributions include the structural basis of regulated N-glycosylation and the dynamics of the ribosome-translocon complex, as well as studies on translocon remodeling during protein synthesis in the ER. He has published extensively in high-impact journals and continues to explore novel aspects of membrane protein synthesis and quality control, contributing to a broader understanding of cell biology and disease mechanisms.
University of California, San Francisco • San Francisco, CA
Conducted research in Biochemistry and Biophysics, focusing on membrane protein biogenesis.
University of Chicago • Chicago, IL
Leading research group in Biochemistry and Molecular Biology, teaching undergraduate and graduate courses.
Department of Philosophy