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Robert H. Mach, Ph.D., is the Britton Chance Professor at the Department of Radiology, Perelman School of Medicine, University of Pennsylvania. His research is primarily focused on the development of radiotracers that investigate the molecular basis of diseases through advanced imaging techniques, specifically positron emission tomography (PET). His key research interests include dopamine D3 receptors, alpha-synuclein related to neurodegeneration and Parkinson’s disease, and PARP-1 in cancer and central nervous system disorders. Dr. Mach is pioneering projects that explore the internalization mechanisms of receptor-mediated pathways and the interactions between small molecules and proteins in cancer cell biology. His laboratory comprises graduate students and postdoctoral researchers working collaboratively on these cutting-edge projects, contributing to significant advancements in the understanding of the interplay between molecular biology and imaging.
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