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Robert P. Ricciardi is a Professor in the Department of Microbiology at the Perelman School of Medicine, University of Pennsylvania. He specializes in the study of oncogenic proteins and their mechanisms by which human viruses exploit cellular functions to regulate gene expression and produce cancer. His research has focused on the role of the E1A-12 protein in tumorigenesis and its interaction with transcription factors such as NF-kB, revealing critical insights into immune evasion by cancerous cells. Additionally, he has investigated the E1A-5 protein's structure and function in gene expression, highlighting its role in stimulating promoters. His recent work involves the processivity factor of KSHV, identifying it as a new target for antiviral drug development. Ricciardi’s laboratory is engaged in advanced methods for understanding these viral mechanisms, contributing valuable knowledge to the field of cancer biology and virology.
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