Dr. Roch Philippe Charles

Biography

Roch-Philippe Charles studied biology at the University of Lausanne, focusing on pharmacology and toxicology. He obtained his PhD under the direction of Dr. Edith Hummler and Prof. Bernard Rossier, investigating the implications of ENaC activator CAP1/Prss8 in perinatal development. He later moved to the Helen Diller Comprehensive Cancer Center at the University of California, San Francisco, where he joined Prof. Martin McMahon’s lab to study the in vivo oncogenic effects of the BRAFV600E mutation. In January 2013, he became an assistant professor at the Institute of Biochemistry and Molecular Medicine at the University of Bern as part of the NCCR-TransCure network. Charles's research aims to bridge laboratory-based drug validation with in vivo approaches, focusing on the role of membrane transporters in mouse models of cancer. The keyword defining his lab is translational biology, with a long-term goal of translating new approaches from laboratory research to treatments in mice, and eventually, human therapies.

Research Interests

Courses