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Ronald T. Raines is the Roger Georges Firmenich Professor of Natural Products Chemistry at the Massachusetts Institute of Technology. His research focuses on the relationship between amino-acid sequences and the three-dimensional structures that encode biological functions. By utilizing techniques from synthetic chemistry and cell biology, Raines’ group aims to illuminate the atomic details of the chemical basis for biological purposes, particularly in the context of protein structure and function. His lab has made significant discoveries, such as the development of RNA-cleaving enzymes that are currently being tested as anti-cancer agents in multi-site clinical trials, and insights into the forces that stabilize proteins. The Raines laboratory is well known for synthesizing hyperstable human-scale synthetic collagens and for developing processes to synthesize proteins that can help catalyze folding and facilitate entry into human cells from crude biomass. Raines' work is characterized by far-reaching hypotheses that integrate diverse techniques and ideas from neighboring scientific disciplines. His lab contributes to widening the interface between chemistry and biology, fostering innovative and impactful research.
Massachusetts Institute of Technology • Cambridge, MA
Roger Georges Firmenich Professor of Natural Products Chemistry, leading research in synthetic chemistry and cell biology.