Generate a tailored SOP for Dr. Ronen Marmorstein. Improve your application with a focused, well-structured draft.
Ronen Marmorstein is a Professor in the Department of Biochemistry and Biophysics and Vice-Chair in the Department of Chemistry at the University of Pennsylvania. His research focuses on the molecular mechanisms of protein post-translational modifications, particularly protein acetylation and phosphorylation, and their roles in chromatin regulation. The Marmorstein laboratory utilizes a wide range of molecular, biochemical, and biophysical research tools, with a special emphasis on macromolecular structure determination through X-ray crystallography and cryo-electron microscopy. Key areas of interest include gene regulatory proteins, signaling kinases, and the implications of protein modifications in cancer and age-related disorders. The lab emphasizes the epigenetic regulation of DNA in the eukaryotic nucleus, investigating how various proteins interact with histones to modulate gene expression. Additionally, it explores the connections between metabolism and epigenetic regulation, focusing on protein acetyltransferases and their substrate specificity. Marmorstein's research contributes to the understanding of cancer biology, particularly in the context of oncogenes and tumor suppressors, aiming to develop small molecule inhibitors for therapeutic applications, with a keen interest in melanoma and MAP kinase signaling pathways.
Department of Biochemistry and Biophysics, University of Pennsylvania • Philadelphia, PA
Leading research on molecular mechanisms of protein modifications and their implications in cancer biology.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.