Dr. Ronjon Chakraverty

Biography

Ronjon Chakraverty is a Professor of Haematology at the University of Oxford, where he leads extensive research in haematopoietic transplantation immunotherapy. He obtained his medical degree from the University of Birmingham and trained in internal medicine and haematology in Cambridge and Oxford. He joined the Weatherall Institute of Molecular Medicine as an MRC Clinical Training Fellow, completing his PhD in 1998. In 2000, he received the LRF Bennett Senior Fellowship in Experimental Haematology, allowing him to join the lab of Professor Megan Sykes at Harvard Medical School, where he focused on mechanisms regulating immune tolerance in reduced intensity transplantation. After moving to University College London in 2005, he developed a translational research program that emphasized T cell immunotherapy, culminating in his appointment as Professor in 2013. There, he played a pivotal role in merging transplant services to create one of Europe’s largest haematopoietic transplantation immunotherapy programs. Since 2020, at the University of Oxford, he has been instrumental in establishing the infrastructure for first-in-human trials of advanced cell gene therapies. His research is centered on understanding the mechanisms dictating the success and failure of T cell immunotherapies in cancer, with a focus on both preclinical models and patient-derived samples. His lab is currently working on targeted approaches to overcome T cell exhaustion and improve antileukemia T cell function, alongside examining the immune-related adverse events such as graft-versus-host disease.

Research Interests